General Information

Methotrexate Ireland (brand names: Rheumatrex, Trexall, Xatmep) holds the main function to interact with special cells located in patient’s body and responsible for growth, mostly the cells reproducing fast. Methotrexate represents an antimetabolite applicable for specific cases of neoplastic sicknesses, rheumatoid arthritis, which prevails among adults and also acute psoriasis.

Methotrexate Ireland is applicable to cure certain cancer types. Moreover, Methotrexate has already demonstrated effectiveness in curing breast cancer. Besides that, this medicine can successfully treat skin cancer. Statistics have shown that head cancer and neck cancer as well as lungs cancer can also be cured with Methotrexate. In addition, Methotrexate can effectively cure acute psoriasis as well as rheumatoid arthritis. Generally, Methotrexate Ireland is taken by patients once other types of approaches and medications have not resulted in any success.

Methotrexate basically interferes with DNA synthesis and is effective against cells, which tend to proliferate faster than normal ones (such cells types generally appear in psoriasis and cancer cases). However, other cells, which are located in gastrointestinal tract, bone marrow, a developing fetus, and the bladder also become sensitive to the effect exerted by Methotrexate Ireland.


Usually, Methotrexate Ireland is not taken on daily basis. Hence, you should take the necessary dosage, which is suitable for current health condition. There are some lethal cases reported among people, who were accidentally having Methotrexate intake on daily basis.

Breastfeeding as well as pregnant patients should abstain from Methotrexate. Methotrexate intake should be avoided in case if a patient suffers from rheumatoid arthritis as well as psoriasis if a patient is currently having liver disease (mostly if it was a result of alcoholism), or else a disorder of blood cell or bone marrow. Contact your pharmacist directly if you start having any abnormal bleeding or bruising and/or signs of possible infections (e.g. chills, fever and/or pain in the body).

Methotrexate Ireland can cause very serious and adverse side effects to such organs as liver. Besides that, lungs and kidneys can also be adversely affected by it. Consult with your doctor if you feel any upper stomach ache, appetite loss, clay-coloured stools, dark urine colour, jaundice, dry cough, blood in urine, shortness of breath, as well as little or no urination.

It is highly advisable not to initiate any treatments with Methotrexate if a patient has allergies to it. Abstain from Methotrexate Ireland to cure psoriasis or rheumatoid arthritis, mostly if you have any of symptoms listed below:

  • a blood cell disorder, like anaemia and/or leukopenia;
  • cirrhosis, alcoholism, or other liver-related diseases;
  • if you are breastfeeding a baby;
  • a bone marrow disorder.

Methotrexate Ireland can in certain circumstances be applied for cancer treatment for patients, who actually have one of the abovementioned symptoms. Your doctor will be the one deciding whether this type of treatment is suitable for you.

To ensure this medication is totally safe for you, contact your doctor if you have:

  • a folate deficiency;
  • kidney disease;
  • stomach ulcers;
  • pneumonia or lung disease;
  • if you are receiving radiation treatments;
  • any type of infection.

Methotrexate Ireland can be a reason for birth defects, which can be caused to a baby that is not born yet. Hereby, it is prohibited to use Methotrexate to cure psoriasis and/or rheumatoid arthritis once you are already pregnant. Inform your doctor without delay if your pregnancy test is positive while taking this drug. You may also require ensuring that you have a negative test for pregnancy prior to initiating the treatment.


Ensure you take Methotrexate Ireland in exact accordance with the prescription and strictly follow all the instructions provided in the prescription leaflet. The amount of Methotrexate as well as corresponding periods of treatment should remain without any changes.

In certain circumstances Methotrexate is taken 1 – 2 times per week, but not every day. So, make sure you reconfirm all the information regarding the dosage and frequency of taking this medicine with your pharmacist.

Measure the necessary amount of liquid medicine with help of available dosing syringe, or else with help of a specifically designed medicine cup and/or a special spoon for dose measurements. If a device for dose measurement is not available, then seek for assistance from your pharmacist. Dosage intake should be maintained on regular basis to achieve the most effective results. Keep monitoring the prescription and ensure it is refilled prior to the moment when the medicine is completely finished.

Side Effects

Seek for immediate medical assistance if you face any of the listed allergies, which can be caused by Methotrexate Ireland:

  • swollen lips, throat, tongue or face;
  • difficulties in breathing;
  • hives.

Stop Methotrexate intake right away and call directly your doctor without any delay if you experience the following:

  • diarrhoea, white-coloured patches or sores appearing inside the mouth and/or on lips, vomiting;
  • shortness of breath, dry cough;
  • quick gain of weight, swollen body parts, little amount of urination or no urination at all;
  • blood in urine and/or stools;
  • seizures (convulsions);
  • easy bruising, pale colour of skin, overall weakness, abnormal bleeding, feeling light-headed;
  • liver problems – pain spreading in the area of upper stomach, frequent nausea, overall tiredness, itching, dark colour of urine, sudden appetite loss, clay-coloured stools,
  • chills, high fever, body pain, general flu symptoms;
  • acute reaction of skin – sore throat, fever, swollen face/tongue, burning feeling in eyes, pain spreading on skin, which is accompanied by a purple or reddish skin rash spreading (mostly in the area of face and/or upper body) and results in peeling of the skin and also blistering.